Advances in Immunology, Vol. 31 by Henry G. Kunkel (ed.), Frank J. Dixon (ed.)

By Henry G. Kunkel (ed.), Frank J. Dixon (ed.)

Show description

Read Online or Download Advances in Immunology, Vol. 31 PDF

Similar science (general) books

Advances in Applied Microbiology, Vol. 35

Meant for researchers in utilized microbiology and environmental engineers, this e-book covers such issues as environmental evaluation of biotechnological strategies and microbial ameliorations of haloaromatic and haloaliphatic compounds.

Frontiers in Brain Repair

Within the rapidly-evolving panorama of neurosciences, it truly is no effortless activity to choose a constrained array of issues to provide in a textual content equivalent to this. the present quantity takes as its objective to supply a consultant survey of the present technological know-how of mind fix for these trying to determine a origin within the box or to refill a previous wisdom base that could have lapsed in its foreign money.

Progressive Concepts for Semantic Web Evolution: Applications and Developments (Advances in Semantic Web & Information Systems Series (Aswis))

Revolutionary ideas for Semantic net Evolution: purposes and advancements unites examine on crucial theories, types, and purposes of Semantic net study. Contributions concentrate on cellular ontologies and brokers, fuzzy databases, and new techniques to retrieval and evaluate within the Semantic internet.

A Biomass Future for the North American Great Plains: Toward Sustainable Land Use and Mitigation of Greenhouse Warming (Advances in Global Change Research)

The North American nice Plains is a massive worldwide breadbasket yet its agriculture is under pressure by way of drought, warmth, harmful winds, soil erosion and declining floor water assets. Biomass construction and processing at the Plains might partly repair a perennial vegetative conceal and create employment possibilities.

Extra resources for Advances in Immunology, Vol. 31

Sample text

For example, release of nonspecific helper factors from the T cell-macrophage interaction that trigger B cells without an I-region restrictive interaction (Section I1I,C). There is no a priori reason why selected T cells cannot interact with the B cell in an I-region-restricted way. B cells take up and handle antigen in a manner analogous to macrophages (Engers and Unanue, 1973), the exception being that only the B cells with specific receptors can interact with antigens, whereas all the macrophages in a population are capable of antigen-binding.

Direct examination of antigen presentation from B cells to T cells has been difficult to test and, in general, has not been critically examined. Technical difficulties in separating macrophages from B cells limit the experiments. The proliferation of T cells was highly favored b y the addition of macrophage-conditioned medium to the culture. More recent results using Ig as antigen support an antigen presenting function of B cells (Chestnut and Grey, 1971). It is possible that the B cell may present antigen, but only for the purpose of receiving back the T cell helper signal that it acquires by direct cell contact.

However, mercaptoethanol enhanced the activity of very small numbers of macrophages added to the culture (Rosenstreich and Mizel, 1978): macrophage-depleted T cells responded marginally to PHA if reconstituted with 1% macrophages, yet 1% macrophages in the presence of mercaptoethanol resulted in a very strong DNA synthesis by the T cells (about 35,000 cpm vs. 3000, respectively) (Fig. 2). , carried out experiments in which the separated T cells or macrophages were pulsed with PHA briefly and then cocultured.

Download PDF sample

Rated 4.84 of 5 – based on 33 votes

Author: admin